Clinical Outcomes Solutions

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Exploring Patient Reported Outcomes at ISOQOL 2021: Enhancing Valid Decision-Making

The ISOQOL 2021 — a pinnacle event in the realm of healthcare — unfolded in October, with online sessions extending through November. Reverberating with the theme "Making valid decisions: Learning from Patient Reported Outcomes," the conference delved into the heart of person-centered care.

ISOQOL's very essence rests in personalizing healthcare by placing patients at its core, a principle strongly resonating with COS's mission. Since 2013, COS has championed innovative science to encapsulate the patient's voice, tirelessly advancing clinical outcomes research.

Stacie Hudgens, the visionary CEO of COS, underscores the significance of actively participating in Quality of Life conferences.

“It is paramount that our team of scientists attend and participate in Quality of Life conferences and meetings, not only to deliver vital thought-leading content to our peers globally but also to learn, discuss and debate the methodological issues that drive innovative research in patient outcomes.”   

Stacie Hudgens
CEO, Clinical Outcomes Solutions

She emphasizes the dual role of contributing pioneering insights to the global community while avidly engaging in methodological discussions that drive groundbreaking research.


This year, COS brought a plethora of thought leadership to the table:

  1. Estimation of meaningful change thresholds for the EORTC QLQ-C30 and QLQ-LC13 in patients with ALK+ non-small cell lung cancer (NSCLC)

  2. The Estimand Framework, Sensitivity Analyses, and Applications in Patient-reported Outcomes

  3. Methods for Determining How Much Missing Data is Tolerable When Scoring a Patient-Reported Outcome (PRO) Measure

  4. An Estimand perspective on the Mixed Model Repeated Measures (MMRM) for the analysis of Longitudinal PRO data in Clinical Trials

  5. Leveraging Social Media for Patient Centric Research in Medical Product Development

  6. Estimated Considerations for Time-to-Event Analysis of Patient-Reported-Outcomes

While the live sessions have drawn to a close, the treasure trove of recorded sessions and on-demand content remains accessible until the end of November, ensuring an extended opportunity for participants to engage and glean insights from this remarkable event.

In its 28th year, the ISOQOL conference is more than just a congregation of minds; it’s a beacon that illuminates the path toward patient-centered care, a principle that COS wholeheartedly champions.

28th Annual Conference | ISOQOL